Angiogenic approaches to meniscal healing
| Autor: | Lynn B. Williams, Adetola B Adesida |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Joint replacement medicine.medical_treatment Osteoarthritis Meniscus (anatomy) Knee Joint Menisci Tibial 03 medical and health sciences 0302 clinical medicine medicine Humans General Environmental Science Meniscectomy Wound Healing business.industry Long term morbidity Semilunar Cartilages 030229 sport sciences Osteoarthritis Knee medicine.disease Surgery Tibial Meniscus Injuries 030104 developmental biology medicine.anatomical_structure General Earth and Planetary Sciences Blood supply business Healthcare system |
| Zdroj: | Injury. 49(3) |
| ISSN: | 1879-0267 |
| Popis: | Meniscal injuries commonly result in osteoarthritis causing long term morbidity, lifelong treatment, joint replacement and significant financial burden to the Canadian healthcare system. Injuries to the outer third of the meniscus often heal well due to adequate blood supply. Healing of injuries in the inner two thirds of the meniscus are often critically retarded due to a lack of blood flow necessitating partial meniscectomy in many instances. Localized angiogenesis in the inner meniscus has yet to be achieved despite a belief that vascularization of these lesions corresponds with meniscal healing. This review briefly summarizes the growth factors that have been assessed for a role in meniscal healing and points to a significant knowledge gap in our understanding of meniscal healing. |
| Databáze: | OpenAIRE |
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