Sleep-Wake Neurochemistry
Autor: | Hans-Peter Landolt, Sebastian C. Holst |
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Rok vydání: | 2022 |
Předmět: |
0301 basic medicine
Sleep Wake Disorders Sleep wake Sleep REM 03 medical and health sciences 0302 clinical medicine Neurochemical Medicine Animals Humans Neurochemistry Wakefulness Brain Chemistry Neurotransmitter Agents business.industry Glutamate receptor General Medicine Sleep in non-human animals Psychiatry and Mental health Clinical Psychology 030104 developmental biology Neuropsychology and Physiological Psychology Neuronal circuits Isolation (psychology) Sleep Stages Neurology (clinical) business Sleep Neuroscience psychological phenomena and processes 030217 neurology & neurosurgery |
Zdroj: | Sleep Medicine Clinics. 17:151-160 |
ISSN: | 1556-407X |
Popis: | Behavioral states naturally alternate between wakefulness and the sleep phases rapid eye movement and nonrapid eye movement sleep. Waking and sleep states are complex processes that are elegantly orchestrated by spatially fine-tuned neurochemical changes of neurotransmitters and neuromodulators including glutamate, acetylcholine, γ-aminobutyric acid, norepinephrine, dopamine, serotonin, histamine, hypocretin, melanin concentrating hormone, adenosine, and melatonin. However, as highlighted in this brief overview, no single neurotransmitter or neuromodulator, but rather their complex interactions within organized neuronal ensembles, regulate waking and sleep states. The neurochemical pathways presented here are aimed to provide a conceptual framework for the understanding of the effects of currently used sleep medications. |
Databáze: | OpenAIRE |
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