Reactivity of asymmetric benzo-condensed diazines with nitrilimine dipoles in the 1,3-dipolar cycloaddition reactions
| Autor: | Anna Maria Almerico, Annalisa Guarcello, Antonino Lauria, Gaetano Dattolo, Gabriella Macaluso |
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| Přispěvatelé: | Lauria, A, Guarcello, A, Macaluso, G, Dattolo, G, Almerico, AM |
| Rok vydání: | 2009 |
| Předmět: |
nitrilimine dipole
Chemistry Nitrilimine 1 3-dipolar cycloaddition reaction Organic Chemistry diazine Settore CHIM/06 - Chimica Organica diastereoselectivity Photochemistry Settore CHIM/08 - Chimica Farmaceutica Biochemistry Cycloaddition chemistry.chemical_compound Dipole Quinoxaline Computational chemistry Drug Discovery 1 3-Dipolar cycloaddition Quinazoline Reactivity (chemistry) |
| Zdroj: | Tetrahedron Letters. 50:7333-7336 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2009.10.062 |
| Popis: | The reactivity of asymmetric benzo-condensed diazines in the 1,3-dipolar cycloaddition reactions with nitrilimines was investigated. The results demonstrated that, at variance with the symmetric quinoxaline, a certain grade of diastereoselectivity emerged. Moreover in the case of the 5-methylquinoxaline and quinazoline a mono-cycloadduct was obtained. |
| Databáze: | OpenAIRE |
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