Willingness to Donate Hair Samples for Research Among People Living with HIV/AIDS Attending a Tertiary Health Facility in Ibadan, Nigeria

Autor: Jacinta N. Nwogu, Baiba Berzins, Chinedum P. Babalola, Samuel O. Ngene, Monica Gandhi, Babafemi Taiwo
Rok vydání: 2019
Předmět:
0301 basic medicine
Male
Health Knowledge
Attitudes
Practice
Biomedical Research
Human immunodeficiency virus (HIV)
HIV Infections
medicine.disease_cause
Tertiary Care Centers
0302 clinical medicine
Health facility
Surveys and Questionnaires
030212 general & internal medicine
Practice
integumentary system
Health Knowledge
Middle Aged
hair collection
Infectious Diseases
HIV/AIDS
Female
Adult
Tissue and Organ Procurement
Immunology
Clinical Sciences
MEDLINE
Nigeria
GeneralLiterature_MISCELLANEOUS
Sociobehavioral Studies
03 medical and health sciences
Acquired immunodeficiency syndrome (AIDS)
Environmental health
Virology
otorhinolaryngologic diseases
medicine
Humans
antiretroviral drugs
ComputingMethodologies_COMPUTERGRAPHICS
adherence monitoring
business.industry
HIV
acceptability rate
medicine.disease
030104 developmental biology
Cross-Sectional Studies
Attitudes
Adherence monitoring
beliefs
sense organs
business
Hair
Zdroj: AIDS Res Hum Retroviruses
AIDS research and human retroviruses, vol 35, iss 7
ISSN: 1931-8405
Popis: The use of hair samples in biomedical research is a rapidly growing field. High acceptability rates for hair collection have been demonstrated in multiple settings. Each setting may have unique issues and, to our knowledge, no previous study has assessed the acceptability of hair sampling for HIV-related research in Nigeria. This study aimed to assess the willingness to donate hair for research among people living with HIV (PLWH). A cross-sectional study was conducted among 381 PLWH in a tertiary institution in Southwest Nigeria, using convenience sampling. An interviewer-administered questionnaire was used to collect data from consenting participants, including a question on willingness to donate hair for research. The mean age of respondents was 42.1 ± 10.5 years and more than three-quarters of the respondents were females. Two hundred and eighty-eight (75.8%) respondents had at least a tertiary education. Only 51.4% of the respondents were willing to donate their hair for research. Possible sample diversion for rituals was the major (60.5%) reason cited for unwillingness to donate hair. In multivariate analysis, respondents with primary education or less exhibited a trend toward being more willing to donate hair than those with secondary education or more (p = .091). Muslims were 1.7 times more willing to donate hair than Christians even after adjusting for other demographic covariates (95% confidence interval: 1.11-2.72); p = .016. There is a moderate willingness to donate hair for research among our population of PLWH in Nigeria. These results underscore the importance of cultural sensitivity and community education when introducing innovative HIV research techniques to new settings.
Databáze: OpenAIRE
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