A Fortifier Comprising Protein, Vitamins, and Calcium-Glycerophosphate for Preterm Human Milk
| Autor: | Vı́ctor Manuel Sánchez-Hidalgo, Guadalupe Matute-González, Ignacia Cisneros-Silva, Bárbara Urquieta-Aguila, Samuel Flores-Huerta, Mariela Bernabe-García |
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| Rok vydání: | 2000 |
| Předmět: |
Retinyl Esters
Whey protein food.ingredient Chemistry Pharmaceutical chemistry.chemical_element Zinc Calcium Phosphates chemistry.chemical_compound Folic Acid food Humans Food science Lactose Infant Nutritional Physiological Phenomena Vitamin A Cholecalciferol Milk Human Chemistry Food additive Phosphorus Infant Newborn Nutritional Requirements Retinol food and beverages Vitamins General Medicine Phosphate Calcium Gluconate Zinc Sulfate Glycerophosphates Food Fortified Female Infant Food Dietary Proteins Diterpenes Dialysis Infant Premature |
| Zdroj: | Archives of Medical Research. 31:564-570 |
| ISSN: | 0188-4409 |
| Popis: | Background The infant's own mother's milk, fortified with proteins, minerals, and vitamins, is considered the best food for low-birth-weight infants. This paper describes the process to obtain a liquid human milk fortifier. Methods The fortifier comprises a protein concentrate, calcium, phosphate, and zinc salts, as well as vitamins A and D. A powdered whey protein extracted from bovine milk was concentrated from 31.5–76.8 g/100 g using repetitive dialysis. The protein concentrate was dissolved in a 0.2 M phosphate buffer pH 7.4 and mixed with calcium-glycerophosphate and calcium-gluconate, vitamins A and D, folic acid, and zinc. Each 10 mL of this liquid fortifier has 0.78 g protein, 53 mg calcium, 36 mg phosphate, and 0.93 mg zinc. Results Repetitive dialysis did not modify the protein structure as demonstrated by electrophoresis. A total of 95% of lactose content was discarded. Enriching human milk using this human milk fortifier increased the concentration per deciliter of all added nutrients; proteins increased from 1.68–2.35 g, calcium from 26–90 mg, and phosphorus, from 15–51 mg. Conclusions A liquid human milk fortifier was successfully manufactured using a noncomplex procedure. An intake of 180–200 mL/kg/day of the fortified human milk by the premature infant would satisfy the infant's nutritional requirements and achieve expected growth and development. |
| Databáze: | OpenAIRE |
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