A case of hirsutism due to bilateral diffuse ovarian Leydig cell hyperplasia in a post-menopausal woman

Autor:	S.E.R.S. Stanaway, D. Bowen-Jones, H.D. Zakhour, G. Spearing, F.S.M. Ali
Rok vydání:	2003
Předmět:	endocrine system medicine.medical_specialty business.industry Hyperandrogenism Urology Post menopausal Hyperplasia medicine.disease Unilateral adrenalectomy Bilateral oophorectomy Leydig cell hyperplasia Endocrinology Internal medicine Internal Medicine medicine business Testosterone hirsutism
Zdroj:	European Journal of Internal Medicine. 14:432-433
ISSN:	0953-6205
DOI:	10.1016/s0953-6205(03)00141-9
Popis:	Hyperandrogenism in females usually results from ovarian or adrenal pathology. We present a case of virilizaton due to very rare bilateral ovarian diffuse interstitial proliferation of Leydig cells with no tumour or hilar cell hyperplasia identified. Interestingly, the case was further complicated by the finding of high levels of testosterone in one adrenal vein on selective venous sampling (SVS), resulting in an unnecessary unilateral adrenalectomy. Further sampling found high levels also in the ovarian veins, and the condition was finally cured by bilateral oophorectomy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e288d5ee78c78e41ef5663a6277c95 https://doi.org/10.1016/s0953-6205(03)00141-9 Zobrazit plný text záznamu Full Text from ScienceDirect