Precision medicine in secondary prevention of ischemic stroke: how may blood-based biomarkers help in clinical routine? An expert opinion
| Autor: | Markus F. F. Arnold, Giulio Bicciato, Mira Katan, Aidan Gebhardt |
|---|---|
| Přispěvatelé: | University of Zurich |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
MEDLINE 610 Medicine & health Brain Ischemia Secondary Prevention Medicine Humans Precision Medicine Intensive care medicine Stroke Expert Testimony Ischemic Stroke Secondary prevention business.industry Blood based biomarkers medicine.disease Precision medicine Clinical routine 10040 Clinic for Neurology Neurology Expert opinion Ischemic stroke Neurology (clinical) business Biomarkers |
| Zdroj: | Current opinion in neurology. 35(1) |
| ISSN: | 1473-6551 |
| Popis: | Purpose of review One in eight patients unfortunately suffers a new stroke within 5 years of their first stroke, even today. Research in precision medicine could lead to a more individualized treatment allocation, possibly achieving lower recurrence rates of ischemic stroke. In this narrative review, we aim to discuss potential clinical implementation of several promising candidate blood biomarkers. Recent findings We discuss specifically some promising blood-based biomarkers, which may improve the identification of underlying causes as well as risk stratification of patients according to their specific cerebrovascular risk factor pattern. Summary Multimodal profiling of ischemic stroke patients by means of blood biomarkers, in addition to established clinical and neuroradiological data, may allow in the future a refinement of decision algorithms for treatment allocation in secondary ischemic stroke prevention. |
| Databáze: | OpenAIRE |
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