Four new fluorenone alkaloids and one new dihydroazafluoranthene alkaloid from Caulophyllum robustum Maxim
| Autor: | Xiao-Ling Wang, Bing-Rui Liu, Shoei-Sheng Lee, Chien-Kuang Chen, Jun-Ru Wang |
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| Rok vydání: | 2011 |
| Předmět: |
DPPH
Stereochemistry Pharmacognosy Plant Roots Berberidaceae Inhibitory Concentration 50 chemistry.chemical_compound Alkaloids Picrates Dibenzazepines Drug Discovery Maxim Medicine Chinese Traditional Pharmacology Fluorenes Molecular Structure biology Alkaloid Biphenyl Compounds General Medicine biology.organism_classification Caulophyllum Caulophyllum robustum chemistry Fluorenone |
| Zdroj: | Fitoterapia. 82:793-797 |
| ISSN: | 0367-326X |
| Popis: | Four new fluorenone alkaloids, caulophylline A-D (1–4), and one new dihydroazafluoranthene alkaloid, caulophylline E (5) were isolated from the roots of Caulophyllum robustum Maxim. Their structures were elucidated by spectroscopic analysis. Among the isolated alkaloids, Caulophylline E showed good scavenging effects against DPPH radical with IC50 of 39 μM. |
| Databáze: | OpenAIRE |
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