CHILDHOOD NON-HODGKIN LYMPHOMA PRESENTING AS HEMOPHAGOCYTIC SYNDROME
| Autor: | Julie Blatt, Harvey J. Hamrick, Diane M. Maia, Brent W. Weston, Tom Belhorn |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Pathology Histiocytosis Non-Langerhans-Cell medicine.medical_treatment Childhood Non-Hodgkin Lymphoma Diagnosis Differential immune system diseases hemic and lymphatic diseases Antineoplastic Combined Chemotherapy Protocols Humans Medicine Serologic Tests Child Rapid response Chemotherapy business.industry Lymphoma Non-Hodgkin Cytogenetics Syndrome Hematology Prognosis medicine.disease Dermatology Lymphoma Histiocytosis Oncology El Niño Pediatrics Perinatology and Child Health Female Lymph Nodes Hemophagocytosis business |
| Zdroj: | Pediatric Hematology and Oncology. 19:45-49 |
| ISSN: | 1521-0669 0888-0018 |
| DOI: | 10.1080/088800102753356185 |
| Popis: | An 8-year-old girl with a progressive systemic hemophagocytic syndrome was found to have non-Hodgkin lymphoma (NHL) after multiple nondiagnostic biopsies. Routine histochemistry and flow cytometry demonstrated this to be a peripheral T-cell process and cytogenetics identified a t(2;5)(p23;q35). An extensive evaluation for an infectious agent failed to identify a pathogen. Treatment according to a standard lymphoma protocol produced a rapid response and the girl remains in remission without evidence of hemophagocytic syndrome 18 months from diagnosis. In children with systemic hemophagocytosis, a diagnosis of NHL should be aggressively pursued. |
| Databáze: | OpenAIRE |
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