SPINDLY, ERECTA, and Its Ligand STOMAGEN Have a Role in Redox-Mediated Cortex Proliferation in the Arabidopsis Root
| Autor: | Hongchang Cui, Jie Li, Yueling Hao, Keiko U. Torii, Pengcheng Wei, Jin Suk Lee, Danyu Kong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Cell signaling
abiotic stress Arabidopsis Receptors Cell Surface Plant Science Protein Serine-Threonine Kinases medicine.disease_cause Plant Roots Arabidopsis thaliana Gene Expression Regulation Plant medicine SPY Molecular Biology cortex proliferation chemistry.chemical_classification Reactive oxygen species redox homeostasis biology Arabidopsis Proteins fungi Hydrogen Peroxide biology.organism_classification Plants Genetically Modified Cortex (botany) Repressor Proteins ROS signaling Biochemistry chemistry Mutation ERECTA Endodermis Signal transduction Reactive Oxygen Species Oxidation-Reduction Oxidative stress Research Article STOMAGEN Signal Transduction |
| Zdroj: | Molecular Plant |
| ISSN: | 1752-9867 1674-2052 |
| Popis: | SUMMARY Reactive oxygen species (ROS) are signaling molecules, but how they are perceived in plants remains unclear. This study showed that cortex proliferation in the Arabidopsis root can be induced by hydrogen peroxide and that the receptor kinase ERECTA and one of its ligands, STOMAGEN, are involved in a signaling pathway that couples ROS sensing with redox-mediated cortex proliferation. This study also revealed a new role for SPINDLY (SPY), a putative O-GlcNAc transferase, in cellular redox homeostasis. Reactive oxygen species (ROS) are harmful to all living organisms and therefore they must be removed to ensure normal growth and development. ROS are also signaling molecules, but so far little is known about the mechanisms of ROS perception and developmental response in plants. We here report that hydrogen peroxide induces cortex proliferation in the Arabidopsis root and that SPINDLY (SPY), an O-linked glucosamine acetyltransferase, regulates cortex proliferation by maintaining cellular redox homeostasis. We also found that mutation in the leucine-rich receptor kinase ERECTA and its putative peptide ligand STOMAGEN block the effect of hydrogen peroxide on root cortex proliferation. However, ERECTA and STOMAGEN are expressed in the vascular tissue, whereas extra cortex cells are produced from the endodermis, suggesting the involvement of intercellular signaling. SPY appears to act downstream of ERECTA, because the spy mutation still caused cortex proliferation in the erecta mutant background. We therefore have not only gained insight into the mechanism by which SPY regulates root development but also uncovered a novel pathway for ROS signaling in plants. The importance of redox-mediated cortex proliferation as a protective mechanism against oxidative stress is also discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect