Synthesis and characterization of glycosylated nano particles

Autor: Vincent Huc, Philippe Roger, Christian Haut, Sébastien Masson, Bénédicte Lepoittevin
Rok vydání: 2006
Předmět:
Zdroj: Scopus-Elsevier
ISSN: 1618-7229
2197-4586
DOI: 10.1515/epoly.2006.6.1.415
Popis: Functionalized polymer nanoparticles have been synthesized by emulsifier-free emulsion polymerization of styrene with amino-functionalized monomers. Two monomers were used: the well-known 2- aminoethylmethacrylate and a new monomer with a styrenic polymerizable function, 4-(2-aminoethylthio)methylstyrene. The latexes were characterized by gravimetry, dynamic light scattering and colorimetric titration in order to obtain the styrene conversion, the hydrodynamic diameter, the particle size distribution and the concentration of surface amino groups, respectively. Then, glycosydic molecules such as maltose, lactose, maltotriose and galactopyranosylethanal were covalently grafted to the nanoparticles by amidation or reductive amination.
Databáze: OpenAIRE