Synthesis of chiral amino acid - derived nitrones and 1,3-dipolar cycloadditions with acrylic acid methyl ester
| Autor: | Lubor Fišera, Zuzana Kopanicková, Iva Blanáriková, Piotr Sałański, Janusz Jurczak, Christian Hametner |
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| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | Scopus-Elsevier ARKIVOC, Vol 2001, Iss 5, Pp 51-59 (2005) |
| ISSN: | 1551-7012 |
| Popis: | The chiral nitrones derived from α-amino acids react with acrylic acid methyl ester to afford the corresponding diastereomeric isoxazolidines 9a-d. The major products are in the C-3/C-4 erythro- and C-3/C-3a trans-configuration. The nitrones 3-8 were prepared from the corresponding α-amino aldehydes, starting from L-phenylalanine and L-valine. |
| Databáze: | OpenAIRE |
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