Relationship between the ST-Segment Resolution and Microvascular Dysfunction in Patients Who Underwent Primary Percutaneous Coronary Intervention
| Autor: | Jong Chun Nah, Jeong-Ha Ha, Kun Joo Rhee, Hyeyoung Lee, Hyo Seung Ahn, Byung Gyu Kim, Young Sup Byun, Gwang Sil Kim, Byung Ok Kim, Sung Woo Cho |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty Article Subject medicine.medical_treatment Infarction 030204 cardiovascular system & hematology Revascularization 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine ST segment 030212 general & internal medicine Myocardial infarction cardiovascular diseases Ejection fraction medicine.diagnostic_test business.industry Percutaneous coronary intervention social sciences medicine.disease eye diseases humanities medicine.anatomical_structure lcsh:RC666-701 Cardiology Clinical Study Cardiology and Cardiovascular Medicine business Electrocardiography geographic locations Artery |
| Zdroj: | Cardiology Research and Practice Cardiology Research and Practice, Vol 2019 (2019) |
| ISSN: | 2090-8016 |
| DOI: | 10.1155/2019/8695065 |
| Popis: | Objectives. Incomplete ST-segment elevation resolution (STR) occasionally occurs despite successful revascularization of epicardial coronary artery after primary percutaneous coronary intervention (PPCI). The aim of this study was to evaluate the relationship between the degree of STR and the severity of microvascular dysfunction. Methods. A total of 73 consecutive patients with ST-segment elevation myocardial infarction (STEMI) who underwent successful PPCI were evaluated. Serial 12-lead electrocardiography was performed at baseline and at 90 minutes after PPCI. Microvascular dysfunction was assessed by index of microvascular resistance (IMR) immediately after PPCI. Results. Patients were classified into 2 groups: 50 patients with complete STR (STR ≥50%) and 23 patients with incomplete STR (STR r = −0.416, P=0.002) and LVEF (r = 0.300, P=0.011). These correlations were only observed in patients with left anterior descending artery (LAD) infarction but not observed in patients with non-LAD infarction. A cutoff IMR value was 27.3 for predicting incomplete STR after PPCI. Conclusion. Incomplete STR after PPCI in patients with STEMI reflects the presence of microvascular and left ventricular dysfunction, especially in patients with LAD infarction. |
| Databáze: | OpenAIRE |
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