Associations among serum folate, waist-to-hip ratio, lipid profile, and eating habits with homocysteine in an elderly Thai population
| Autor: | Rungsunn Tungtrongchitr, Ngamphol Soonthornworasiri, Dumrongkiet Arthan, Alisara Wongsutthilerd, Amornrat Aroonnual, Wanyarat Nakosiri, Somchai Pooudoung, Sarunya Kaewprasert, Arth Nana, Chaowanee Chupeerach, Chirawat Paratthakonkun, Siriporn Chanchai, Pattaneeya Prangthip, Yaovamarn Chantaranipapong |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Homocysteine Endocrinology Diabetes and Metabolism Hyperhomocysteinemia Medicine (miscellaneous) Older population chemistry.chemical_compound Folic Acid Waist–hip ratio Serum folate Internal medicine Thai population medicine Humans Eating habits Aged Nutrition and Dietetics Serum folate level medicine.diagnostic_test Waist-Hip Ratio business.industry Feeding Behavior General Medicine Middle Aged Thailand Lipids Vitamin B 12 Cross-Sectional Studies Endocrinology chemistry business Lipid profile |
| Zdroj: | International Journal for Vitamin and Nutrition Research. 89:246-254 |
| ISSN: | 1664-2821 0300-9831 |
| DOI: | 10.1024/0300-9831/a000402 |
| Popis: | Abstract. A lower serum folate level is common in older populations and is associated with increased serum homocysteine concentration. In turn, an elevated homocysteine level is associated with increased risk of cardiovascular disease and age-related diseases. Contemporary studies of folate and dietary risk factors for cardiovascular disease among the elderly population in Thailand are lacking. This cross-sectional study aimed to investigate the relationships among serum folate, homocysteine level, and nutritional status in the elderly Thai. Three hundred individuals, aged 60 years and over, underwent anthropometric and physiological measurements, and biochemical parameters, and eating habits were also determined. Folate insufficiency was found in approximately 35% of subjects. Folate and homocysteine showed a significant inverse correlation. Serum homocysteine levels rose with increasing age. Folate deficiency and high waist-to-hip ratio were associated with 7-fold and 2.5-fold increased risk for hyperhomocysteinemia, respectively. There were positive correlations between homocysteine and waist-to-hip ratio and systolic blood pressure, but a negative correlation between homocysteine and high-density lipoprotein ( r = −0.239, p |
| Databáze: | OpenAIRE |
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