Rare Presentation of Rosai-Dorfman Disease Mimicking a Cervical Intramedullary Spinal Cord Tumor
| Autor: | Tamadur Mahasneh, Sue-Ellen Holmes, Mohamed El Molla, Darweesh Al-Khawaja |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Male
Pathology medicine.medical_specialty Biopsy Central nervous system Diagnosis Differential Lesion Cervical lymphadenopathy medicine Humans Spinal Cord Neoplasms Rosai–Dorfman disease Aged business.industry Sinus Histiocytosis with Massive Lymphadenopathy medicine.disease Spinal cord Magnetic Resonance Imaging Histiocytosis Spinal cord tumor medicine.anatomical_structure Cervical Vertebrae Surgery Neurology (clinical) Histiocytosis Sinus medicine.symptom business |
| Zdroj: | World Neurosurgery. 81:442.e7-442.e9 |
| ISSN: | 1878-8750 |
| DOI: | 10.1016/j.wneu.2013.01.002 |
| Popis: | Background Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy, is a rare, benign, lymphoproliferative disorder that commonly manifests as a massive painless cervical lymphadenopathy with associated fever and weight loss. Central nervous system involvement is extremely rare, and cervical spinal cord manifestation has not been reported. Methods A 76-year-old man presented with a 10-week history of right hemiparesis. Magnetic resonance imaging identified an enhancing cervical intramedullary lesion consistent with a primary spinal cord tumor. Results Histopathology revealed intramedullary histiocytosis. Conclusions This cervical presentation of Rosai-Dorfman disease with central nervous system involvement suggests variation in the clinical manifestations of the disease, necessitating greater surgical awareness. |
| Databáze: | OpenAIRE |
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