Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018
| Autor: | Christian E. Lange, Karen Saylors, Moctar M M Mouiche, David J McIver, James A. Ayukekbong, Edward M. Rubin, Valantine Ngum Ndze, Matthew LeBreton, Julius Nwobegahay, Ubald Tamoufe, Amethyst Gillis, Bisse Albert, Victorine T. Maptue, Nkom F Ntumvi |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Serotype Adult Male Adolescent viruses 030231 tropical medicine Disease Dengue virus medicine.disease_cause Microbiology Polymerase Chain Reaction Virus Dengue fever Dengue 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Virology parasitic diseases medicine Prevalence Humans Cameroon Flavivirus RNA biology virus diseases biochemical phenomena metabolism and nutrition 030108 mycology & parasitology Dengue Virus biology.organism_classification medicine.disease Flavivirus Infectious Diseases RNA Viral Female Malaria |
| Zdroj: | Vector borne and zoonotic diseases (Larchmont, N.Y.). 20(4) |
| ISSN: | 1557-7759 |
| Popis: | Dengue fever is an understudied disease in many parts of Africa and little is known about its prevalence in Cameroon. We tested blood from 629 individuals from the South Region of Cameroon, collected over the course of one year, for flavivirus RNA using conventional broad range PCR. Flavivirus RNA corresponding to dengue virus (DENV) serotype 1 was identified in two individuals who were also diagnosed with malaria. This finding confirms previous reports that indicate the presence of low-level circulation of DENV in Cameroon and supports the concern that dengue fever may be underdiagnosed due to more prevalent diseases that have similar symptomology and insufficient diagnostic capacity. |
| Databáze: | OpenAIRE |
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