Clinicopathological features and prognosis of triple-negative breast cancer: a comparison between younger (60) and elderly (≥60) patients

Autor: R. Li, J.D. Qiu, J.D. Wang, X.Y. Xue
Rok vydání: 2015
Předmět:
Zdroj: European journal of cancer care. 25(6)
ISSN: 1365-2354
Popis: Triple-negative breast cancer (TNBC) has attracted more attention both clinically and experimentally because of its high-risk biological characteristics and lacking of effective treatment method. The tumour characteristics, patterns of recurrence and metastasis, therapy methods and prognosis in younger TNBC patients have been widely formulated, but the relevant data of the elderly people are lacking. We conducted this retrospective study to compare and analyse the above-related characteristics between the younger and elderly patients with TNBC to estimate the relevance for the elderly TNBC patients. A total of 1489 female patients with primary breast cancer were diagnosed and treated at the department of General Surgery, the Chinese PLA General Hospital, China, from January 2004 to December 2008. In the 1489 patients, 302 patients (20.28%) with TNBC histopathologically confirmed were retrospectively analysed. The 302 TNBC patients were divided into two groups: the younger (
Databáze: OpenAIRE