Clinicopathological features and prognosis of triple-negative breast cancer: a comparison between younger (60) and elderly (≥60) patients
Autor: | R. Li, J.D. Qiu, J.D. Wang, X.Y. Xue |
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Rok vydání: | 2015 |
Předmět: |
0301 basic medicine
Oncology Adult medicine.medical_specialty China medicine.medical_treatment Aftercare Antineoplastic Agents Triple Negative Breast Neoplasms Kaplan-Meier Estimate Metastasis 03 medical and health sciences Young Adult 0302 clinical medicine Breast cancer Age Distribution Internal medicine medicine Humans General hospital Triple-negative breast cancer Aged Retrospective Studies Aged 80 and over Chemotherapy business.industry Retrospective cohort study Middle Aged medicine.disease Prognosis Combined Modality Therapy humanities Surgery Radiation therapy 030104 developmental biology 030220 oncology & carcinogenesis Clinicopathological features Female Neoplasm Recurrence Local business |
Zdroj: | European journal of cancer care. 25(6) |
ISSN: | 1365-2354 |
Popis: | Triple-negative breast cancer (TNBC) has attracted more attention both clinically and experimentally because of its high-risk biological characteristics and lacking of effective treatment method. The tumour characteristics, patterns of recurrence and metastasis, therapy methods and prognosis in younger TNBC patients have been widely formulated, but the relevant data of the elderly people are lacking. We conducted this retrospective study to compare and analyse the above-related characteristics between the younger and elderly patients with TNBC to estimate the relevance for the elderly TNBC patients. A total of 1489 female patients with primary breast cancer were diagnosed and treated at the department of General Surgery, the Chinese PLA General Hospital, China, from January 2004 to December 2008. In the 1489 patients, 302 patients (20.28%) with TNBC histopathologically confirmed were retrospectively analysed. The 302 TNBC patients were divided into two groups: the younger ( |
Databáze: | OpenAIRE |
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