Mortality in broiler chicks on feed amended withFusarium proliferatum culture material or with purified fumonisin B1 and moniliformin
| Autor: | Glenn A. Bennett, William B. Buck, J. L. Richard, Mary Ann Dombrink-Kurtzman, L. M. Cote, Tariq Javed |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
Fusarium Veterinary (miscellaneous) Fusarium proliferatum Weight Gain Fumonisins Applied Microbiology and Biotechnology Microbiology Toxicology chemistry.chemical_compound Animal science Fumonisin Animals Mycotoxin Poultry Diseases Fumonisin B2 Fumonisin B1 biology Broiler food and beverages Mycotoxins biology.organism_classification Animal Feed chemistry Culture Media Conditioned Chickens Agronomy and Crop Science Moniliformin Cyclobutanes |
| Zdroj: | Mycopathologia. 123:171-184 |
| ISSN: | 1573-0832 0301-486X |
| DOI: | 10.1007/bf01111269 |
| Popis: | Two hundred twenty-eight male chicks (Columbia x New Hampshire) were given feed amended with autoclaved culture material (CM) of Fusarium proliferatum Containing fumonisin B1 (FB1), fumonisin B2 (FB2) and moniliformin in 3 separate feeding trials. Purified FB1 and moniliformin were given separately and in combination in a fourth feeding trial. Birds were given amended rations at day 1 (Trial 1 and 4), day 7 (Trial 2), and day 21 (Trial 3) and their respective ration was given for 28 days (Trial 1), 21 days (Trial 2), 7 days (Trial 3), and 14 days (Trial 4). FB1 concentrations were 546, 193, and 61 ppm; FB2 were 98, 38 and 14 ppm; and moniliformin were 367, 193, and 66 ppm in the first 3 feeding trial regimens. Chicks in Trial 4 were given dietary concentrations of purified FB1 at 274 and 125 ppm, and moniliformin at 154 and 27 ppm. FB1 and moniliformin, both alone and in combination, produced dose-responsive clinical signs, reduced weight gains and mortality in chicks. Age of birds given amended feeds had little difference in the clinical response; however, those given the rations from days 7 or 21 were slightly less susceptible than those given rations beginning at 1 day of age. Additive effects were noted when the toxins were given in combination. When toxins were given separately, adverse effects took longer to occur. A system to monitor pattern and rate of defecation (RD) was developed for assessing the chicks' approach to feed, water and heat source as illness progressed. Our results indicate that chicks fed corn heavily infected with F. proliferatum under field conditions could suffer acute death similar to that described for 'spiking mortality syndrome' during the first 3 weeks of age. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink