Seasonal dynamics of human retinol status in mobile pastoralists in Chad
| Autor: | Jan Hattendorf, Jakob Zinsstag, D. M. Daugla, Bongo Naré Richard Ngandolo, M. Bechir, Lisa Crump |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Critical time Chad Veterinary (miscellaneous) Pastoralism Drinking Biology Logistic regression 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Animal science Risk Factors Dry season Prevalence medicine Animals Humans 030212 general & internal medicine Animal Husbandry Vitamin A Transients and Migrants 030109 nutrition & dietetics Human blood Vitamin A Deficiency Ecology Retinol Seasonality medicine.disease Agricultural Workers' Diseases Arabs Vitamin A deficiency Lakes Cross-Sectional Studies Logistic Models Milk Infectious Diseases chemistry Insect Science Female Parasitology Seasons |
| Zdroj: | Acta Tropica. 166:280-286 |
| ISSN: | 0001-706X |
| DOI: | 10.1016/j.actatropica.2016.11.040 |
| Popis: | Vitamin A deficiency is a prevalent public health problem in Africa and South-East Asia, although national population based surveys are lacking in many countries. This study investigated seasonal variation of human retinol concentrations in Chadian mobile pastoralists to identify critical time periods for interventions addressing vitamin A deficiency. The repeated cross-sectional study design used convenience sampling during three seasons to include 327 Fulani, Gorane and Arab adult mobile pastoralists in nine camps in the Lake Chad area. Human blood and pooled cattle milk retinol concentrations were rapidly assessed by portable flourometer (iCheck™). Linear regression models with random effects for correlation within camps were applied with human retinol concentration as outcome. Logistic regression models, with camp as random effect, were evaluated for the outcome human retinol deficiency. Human seasonal means were 2.14μmol/L (95% CI 1.82-2.46) in rainy, 0.99μmol/L (95% CI 0.91-1.07) in cold and 1.86μmol/L (95% CI 1.63-2.09) in dry season. Retinol concentration and deficiency varied according to season and ethnic group. Average values were highest in Gorane during rainy and in Fulani in the cold and dry seasons. Arabs had lowest average values in all seasons. Retinol deficiency ( |
| Databáze: | OpenAIRE |
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