Comparative analysis of screening models for undiagnosed diabetes in Mexico
| Autor: | Gerardo J. Félix-Martínez, José Rafael Godínez-Fernández |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Waist Endocrinology Diabetes and Metabolism Adult population Early detection 030209 endocrinology & metabolism Disease 03 medical and health sciences 0302 clinical medicine Endocrinology Diabetes mellitus Environmental health medicine Diabetes Mellitus Humans Mass Screening 030212 general & internal medicine Mexico National health Nutrition and Dietetics business.industry Middle Aged Models Theoretical medicine.disease Nutrition Surveys Multivariate logistic regression model Female Undiagnosed diabetes business |
| Zdroj: | Endocrinología, Diabetes y Nutrición (English ed.). 67:333-341 |
| ISSN: | 2530-0180 |
| DOI: | 10.1016/j.endien.2019.08.009 |
| Popis: | Background It is estimated that 37% of Mexican adults have undiagnosed diabetes, and are therefore at high risk of developing the severe and devastating complications associated to it. In recent years, a variety of screening tools based on the characteristics of the adult Mexican population have been proposed in order to reduce the negative effects of the disease. Objectives To assess the performance of screening models to diagnose diabetes in the Mexican adult population and to propose a screening model based on HbA1c measurements. Materials and methods Data from the 2016 Halfway National Health and Nutrition Survey (NHNS) were used to assess the screening models and to develop and validate the proposed 2016 NHNS model, built using a multivariate logistic regression model. Explanatory variables included in the 2016 NHNS 2016 model were selected through a stepwise backward procedure, using sensitivity and specificity as performance indicators. Results Of the screening models assessed, only the model based on the 2006 NHNS survey showed a performance consistent with previous reports. The proposed 2016 NHNS model included age, waist circumference, and systolic blood pressure as explanatory variables and showed a sensitivity of 0.72 and a specificity of 0.80 in the validation data set. Conclusions Age, waist circumference, and systolic blood pressure are variables of special importance for early detection of undiagnosed diabetes in Mexican adults. Based on the consistent performance of the 2006 NHNS model in different data sets, its use as a screening tool for adults with undiagnosed diabetes in Mexico is recommended. |
| Databáze: | OpenAIRE |
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