In Vitro Evaluation of Sub-Lethal Concentrations of Plant-Derived Antifungal Compounds on FUSARIA Growth and Mycotoxin Production
| Autor: | Assetou Bara, Caterina Morcia, Giorgio Tumino, Valeria Terzi, Nesrine Salhi, Roberta Ghizzoni |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Fusarium Antifungal Agents natural products 030106 microbiology Drug Evaluation Preclinical Pharmaceutical Science Biology Citral Analytical Chemistry lcsh:QD241-441 03 medical and health sciences chemistry.chemical_compound lcsh:Organic chemistry Vomitoxin Drug Discovery Botany Fusarium langsethiae Oils Volatile Animals Humans Food science Physical and Theoretical Chemistry Mycotoxin Plant Extracts Communication Organic Chemistry HT-2 toxins food and beverages Mycotoxins biology.organism_classification Fusarium sporotrichioides Fungicide Fusarium graminearum 030104 developmental biology chemistry Chemistry (miscellaneous) T-2 deoxynivalenol (DON) Molecular Medicine Cuminaldehyde |
| Zdroj: | Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry Molecules, Vol 22, Iss 8, p 1271 (2017) |
| ISSN: | 1420-3049 |
| Popis: | Phytopathogenic fungi can lead to significant cereal yield losses, also producing mycotoxins dangerous for human and animal health. The fungal control based on the use of synthetic fungicides can be complemented by "green" methods for crop protection, based on the use of natural products. In this frame, the antifungal activities of bergamot and lemon essential oils and of five natural compounds recurrent in essential oils (citronellal, citral, cinnamaldehyde, cuminaldehyde and limonene) have been evaluated against three species of mycotoxigenic fungi (Fusarium sporotrichioides, F. graminearum and F. langsethiae) responsible for Fusarium Head Blight in small-grain cereals. The natural products concentrations effective for reducing or inhibiting the in vitro fungal growth were determined for each fungal species and the following scale of potency was found: cinnamaldehyde > cuminaldehyde > citral > citronellal > bergamot oil > limonene > lemon oil. Moreover, the in vitro mycotoxin productions of the three Fusaria strains exposed to sub-lethal concentrations of the seven products was evaluated. The three fungal species showed variability in response to the treatments, both in terms of inhibition of mycelial growth and in terms of modulation of mycotoxin production that can be enhanced by sub-lethal concentrations of some natural products. This last finding must be taken into account in the frame of an open field application of some plant-derived fungicides. |
| Databáze: | OpenAIRE |
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