Etiology of Pediatric Bacterial Meningitis Pre- and Post-PCV13 Introduction Among Children Under 5 Years Old in Lomé, Togo
| Autor: | Joseph Nsiari-Muzeyi Biey, Mawussi Godonou, Abdul Karim Sesay, Novissi Tsogbale, Martin Antonio, Leopold D. Tientcheu, Bernard Ntsama, Peter Sylvanus Ndow, Dadja Essoya Landoh, Segla D. Tigossou, Madikay Senghore, Archibald Worwui, Brenda Kwambana-Adams, Yawo Dzayissè Atakouma, Djatougbe Ayaovi Elie Akolly, Rowan E Bancroft, Jason M. Mwenda, Anoumou Dagnra, Enyonam Tsolenyanu, M Fiawoo |
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| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine Microbiology (medical) Pediatrics medicine.medical_specialty vaccine impact 030106 microbiology Supplement Articles Neisseria meningitidis Serogroup medicine.disease_cause Meningitis Bacterial Haemophilus influenzae Hospitals University Pneumococcal Vaccines 03 medical and health sciences 0302 clinical medicine Streptococcus pneumoniae Prevalence medicine Humans 030212 general & internal medicine Whole Genome Sequencing business.industry Incidence Vaccination Infant Newborn meningitis Infant Outbreak Pneumococcus medicine.disease 3. Good health Bacterial vaccine pediatric Infectious Diseases Togo Child Preschool Female business Sentinel Surveillance Meningitis MenAfriVac |
| Zdroj: | Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1093/cid/ciz473 |
| Popis: | Background Pediatric bacterial meningitis (PBM) causes severe morbidity and mortality within Togo. Thus, as a member of the World Health Organization coordinated Invasive Bacterial Vaccine Preventable Diseases network, Togo conducts surveillance targeting Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae, at a sentinel hospital within the capital city, Lomé, in the southernmost Maritime region. Methods Cerebrospinal fluid was collected from children Streptococcus pneumoniae was the predominant pathogen responsible for pediatric bacterial meningitis during longitudinal sentinel surveillance within Togo, from 2010 to 2016. However, pneumococcal meningitis cases decreased by 88.1% (52/59) postvaccine introduction; from 59 cases prevaccine introduction to 7 cases postvaccine introduction. |
| Databáze: | OpenAIRE |
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