Analysis of peripheral doses for base of tongue treatment by linear accelerator and helical TomoTherapy IMRT
| Autor: | Howard R. Elson, Michael Lamba, Brian Richard Bennett |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Organs at Risk
medicine.medical_specialty medicine.medical_treatment Tomotherapy Linear particle accelerator peripheral dose Tongue Medicine Humans Radiation Oncology Physics Radiology Nuclear Medicine and imaging Head and neck Instrumentation risk Radiation intensity‐modulated radiation therapy business.industry Phantoms Imaging Radiotherapy Planning Computer-Assisted Radiotherapy Dosage whole‐body dose Peripheral Tongue Neoplasms radiation dosimetry Radiation therapy medicine.anatomical_structure Anthropomorphic phantom Thermoluminescent Dosimetry Thermoluminescent dosimeter Radiology Radiotherapy Intensity-Modulated Particle Accelerators business Nuclear medicine Tomography Spiral Computed |
| Zdroj: | Journal of Applied Clinical Medical Physics |
| ISSN: | 1526-9914 |
| Popis: | The purpose of this study was to compare the peripheral doses to various organs from a typical head and neck intensity‐modulated radiation therapy (IMRT) treatment delivered by linear accelerator (linac) and helical TomoTherapy. Multiple human CT data sets were used to segment critical structures and organs at risk, fused and adjusted to an anthropomorphic phantom. Eighteen contours were designated for thermoluminescent dosimeter (TLD) placement. Following the RTOG IMRT Protocol 0522, treatment of the primary tumor and involved nodes (PTV70) and subclinical disease sites (PTV56) was planned utilizing IMRT to 70 Gy and 56 Gy. Clinically acceptable treatment plans were produced for linac and TomoTherapy treatments. TLDs were placed and each treatment plan was delivered to the anthropomorphic phantom four times. Within 2.5 cm (one helical TomoTherapy field width) superior and inferior to the field edges, normal tissue doses were on average 45% lower using linear accelerator. Beyond 2.5 cm, the helical TomoTherapy normal tissue dose was an average of 52% lower. The majority of points proved to be statistically different using the Student's t‐test with p |
| Databáze: | OpenAIRE |
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