Effects of HIV triple therapy on methadone levels
| Autor: | Edward Nunes, Evaristo O. Akerele, Herbert Kleber, Frances Rudnick Levin, Ronald Brady |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Anti-HIV Agents Human immunodeficiency virus (HIV) Medicine (miscellaneous) HIV Infections medicine.disease_cause Internal medicine medicine Potency Humans Drug Interactions Aged Aids patients Acquired Immunodeficiency Syndrome business.industry Heroin Dependence Middle Aged Psychiatry and Mental health Clinical Psychology Cross-Sectional Studies Anesthesia Hiv patients Drug Therapy Combination Female business Methadone medicine.drug |
| Zdroj: | The American journal on addictions. 11(4) |
| ISSN: | 1055-0496 |
| Popis: | There is a belief among methadone patients that triple therapy for HIV reduces methadone potency. This cross-sectional study compared the rate of methadone metabolism (peak-trough blood levels) in two groups of methadone-maintained patients, AIDS patients receiving triple therapy (N = 17), and HIV patients without triple therapy (N = 19). These preliminary findings suggest that triple therapy may increase the rate of methadone metabolism, though further studies are warranted. |
| Databáze: | OpenAIRE |
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