Use of a drug containing ornidazole-neomycin–prednisolone–econazole for the empirical treatment of vaginal infections
| Autor: | Tatyana V. Zakharova, Valerii G. Volkov |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Econazole lcsh:Gynecology and obstetrics 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine non-specific vaginitis lcsh:RG1-991 Vaginitis ornidazole business.industry elzhina Ornidazole neomycin Obstetrics and Gynecology prednisolone econazole medicine.disease Dermatology medicine.anatomical_structure 030220 oncology & carcinogenesis Prednisolone Vagina Etiology Itching medicine.symptom Bacterial vaginosis business bacterial vaginosis medicine.drug |
| Zdroj: | Гинекология, Vol 22, Iss 4, Pp 28-32 (2020) |
| ISSN: | 2079-5831 2079-5696 |
| Popis: | Relevance. Empirical treatment of vaginitis is indicated due to its polymicrobial etiology and limited microbiological analysis. The aim of the study was to study the combination of ornidazoleneomycinprednisoloneeconazole (ONPE, Elzhina) as a first-line drug for local treatment of patients with various forms of non-specific vaginitis. Materials and methods. The study included 55 non-pregnant women aged 18 to 50 years (381.5 years) who had clinical and laboratory signs of acute vaginitis. Results. All patients at the initial treatment complained of pathological discharge, 47 (85.5%) noted itching, burning, pain in the genital area of various degrees of severity, 17 (30.9%) discomfort when urinating, 9 (16.4%) unpleasant smell, 8 (14.5%) dyspareunia, 4 (2.2%) complained of sensations of a foreign body in the vagina. The clinical and laboratory effectiveness of treatment was 89.1% (49). In 6 (10.9%) patients, clinical improvement was noted, with the remaining laboratory signs of aerobic vaginitis. Conclusion. The new combination of ornidazoleneomycinprednisoloneeconazole (ONPE, Elzhina ) has a good efficacy and safety profile and can be used to initiate empirical treatment of non-specific inflammatory diseases of the lower genital tract. |
| Databáze: | OpenAIRE |
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