Strongyloides stercoralis hyperinfection associated with human T cell lymphotropic virus type-1 infection in Peru
| Autor: | Raúl Tello, Eduardo Gotuzzo, D M Watts, David O. Freedman, Infante R, Alvarez H, Angelica Terashima |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Helminthiasis Biology Asymptomatic Virus Strongyloides stercoralis Feces Sex Factors Seroepidemiologic Studies Virology Peru medicine Animals Humans Human T cell lymphotropic virus type 1 Intestinal Diseases Parasitic Age Factors Case-control study medicine.disease biology.organism_classification HTLV-I Infections HTLV-I Antibodies Infectious Diseases Strongyloidiasis Case-Control Studies Strongyloides Immunology Female Parasitology medicine.symptom |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | A study was conducted in Lima, Peru to determine if patients with Strongyloides hyperinfection had human T cell lymphotropic virus type-1 (HTLV-I) infection. The study included patients with Strongyloides hyperinfection and a control group consisted of sex- and age-matched asymptomatic healthy individuals whose stools were negative for Strongyloides. A third group included patients with intestinal strongyloidiasis. Sera from each study subject were tested for HTLV-1/2I by an ELISA and Western blot. The HLTV-1 infection rates (85.7%, 18 of 21) were significantly (P0.001) associated with Strongyloides hyperinfection compared with the control group (4.7%, 1 of 21). The HTLV-1 rate (10%, 6 of 62) for patients with intestinal strongyloidiasis was significantly (P0.001) lower than patients with Strongyloides hyperinfection, but did not differ significantly (P0.05) from the control group. The association of HTLV-1 infection was observed among 17 of 19 patients more than 20 years of age and one of two younger patients. None had HTLV-2 infection. In conclusion, Strongyloides hyperinfection among Peruvian patients was highly associated with HTLV-1 infection. |
| Databáze: | OpenAIRE |
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