Arsenic, cadmium, lead, and chromium in well water, rice, and human urine in Sri Lanka in relation to chronic kidney disease of unknown etiology
| Autor: | S. K. Yatigammana, Shiori Nagasawa, Ayuri Motoyama, A. A. G. D. Amarasooriya, G. G. Tushara Chaminda, Yuka Serikawa, H M Ayala S Herath, S. K. Weragoda, Tomonori Kawakami |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Chromium
inorganic chemicals 0301 basic medicine Microbiology (medical) Water Wells chemistry.chemical_element Urine 010501 environmental sciences 01 natural sciences Arsenic 03 medical and health sciences Metals Heavy medicine Humans Renal Insufficiency Chronic Waste Management and Disposal Sri Lanka 0105 earth and related environmental sciences Water Science and Technology Cadmium Public Health Environmental and Occupational Health Oryza Heavy metals Environmental Exposure medicine.disease 030104 developmental biology Infectious Diseases chemistry Environmental chemistry Sri lanka Kidney disease |
| Zdroj: | Journal of Water and Health. 16:212-222 |
| ISSN: | 1996-7829 1477-8920 |
| DOI: | 10.2166/wh.2018.070 |
| Popis: | Chronic kidney disease of unknown etiology (CKDu) is spreading gradually in Sri Lanka. In the current research, 1,435 well water samples from all 25 districts of Sri Lanka, 91 rice samples, and 84 human urine samples from both CKDu-endemic and non-endemic areas in Sri Lanka were analyzed for arsenic, cadmium, lead, and chromium to detect whether toxic elements could be a cause of CKDu. The liver-type fatty acid binding protein (L-FABP) concentration and arsenic, cadmium, lead, and chromium concentrations of the urine samples were analyzed to determine the relation of L-FABP with arsenic, cadmium, lead, and chromium. High concentrations of arsenic, cadmium, lead, and chromium were not detected in the well water samples from CKDu-endemic areas. Arsenic, cadmium, and lead contents in the rice samples from both CKDu-endemic and non-endemic areas were well below the Codex standard. There were no relationships between the L-FABP concentration and concentrations of arsenic, cadmium, lead, and chromium in urine. In addition, arsenic, cadmium, lead, and chromium concentrations in human urine samples from CKDu-endemic areas were not significantly different from those from non-endemic areas. These findings indicated that arsenic, cadmium, lead, and chromium could not cause CKDu. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|