Anxiety Independently Contributes to Severity of Freezing of Gait in People With Parkinson’s Disease
| Autor: | Lorena R.S. Almeida, Elen Beatriz Pinto, Carolina Silva, Dandara Moreira, Taísa Nogueira, Milla Pimenta, Guilherme T. Valenca |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Levodopa medicine.medical_specialty Parkinson's disease Hospital Anxiety and Depression Scale Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation medicine Humans Gait Disorders Neurologic Depression (differential diagnoses) Aged Aged 80 and over 030214 geriatrics business.industry Montreal Cognitive Assessment Parkinson Disease Middle Aged medicine.disease Explained variation Anxiety Disorders Gait Psychiatry and Mental health Anxiety Female Neurology (clinical) medicine.symptom business human activities 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | The Journal of Neuropsychiatry and Clinical Neurosciences. 31:80-85 |
| ISSN: | 1545-7222 0895-0172 |
| Popis: | Freezing of gait is a disabling feature of Parkinson's disease, and it has been shown that nonmotor symptoms, such as anxiety and cognitive impairment, may be involved in the pathophysiology of the phenomenon. However, the association between freezing of gait severity and nonmotor symptoms is yet to be determined. Therefore, the overall aim of this study was to determine factors that contribute to severity of freezing of gait in people with Parkinson's disease. Participants (N=78) were assessed by disease-specific and self-report measures, including the Hospital Anxiety and Depression Scale (HADS), the Montreal Cognitive Assessment, and the Freezing of Gait Questionnaire (FOG-Q). Participants were classified as "freezers" if they scored ≥1 on item 3 of the FOG-Q; the sum of items 3-6 was used to determine freezing of gait severity. Freezers (N=27) showed higher scores on the HADS anxiety (p=0.002) and HADS depression (p=0.006) subscales. A multivariate linear model showed that disease severity (as measured by using the modified Hoehn and Yahr scale) accounted for 31% of the variance in FOG-Q severity scores (p |
| Databáze: | OpenAIRE |
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