Multiphysics Finite-Element Modeling of the Neuron/Electrode Electrodiffusive Interaction

Autor:	Federico Leva, Claudio Verardo, Leandro Julian Mele, Pierpaolo Palestri, Luca Selmi
Přispěvatelé:	RS: FSE MaCSBio, Maastricht Centre for Systems Biology
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	extracellular sensing FEM neural recording RECORDINGS Hodgkin-Huxley EQUIVALENT-CIRCUIT neural signal transduction
Zdroj:	2022 IEEE SENSORS, 1-4 STARTPAGE=1;ENDPAGE=4;TITLE=2022 IEEE SENSORS 2022 IEEE Sensors
ISSN:	1930-0395
DOI:	10.1109/sensors52175.2022.9967049
Popis:	Understanding the biological-electrical transduction mechanisms is essential for reliable neural signal recording and feature extraction. As an alternative to state-of-the-art lumped-element circuit models, here we adopt a multiscale-multiphysics finite-element modeling framework. The model couples ion transport with the Hodgkin-Huxley model and the readout circuit, and is used to investigate a few relevant case studies. This approach is amenable to explore ion transport in the extracellular medium otherwise invisible to circuit model analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55ec5dc29263fa85d22881f40a59b2d https://doi.org/10.1109/sensors52175.2022.9967049 Zobrazit plný text záznamu