COVID-19 reinfection: Linked possibilities and future outlook

Autor: Hannah Jose, Reshma Prasad, Ekta Krishna, Vineet Kumar Pathak, M Mohan Kumar
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Family Medicine and Primary Care, Vol 9, Iss 11, Pp 5445-5449 (2020)
Journal of Family Medicine and Primary Care
ISSN: 2249-4863
Popis: SARS-CoV-2 is the third major coronavirus epidemic to affect humans. There had been multiple instances of patients turning positive after recovering from SARS-2-CoV infection. Though many different theories emerge, false positive RT-PCR is logically the foremost cause and there is a general consensus that during quarantine re-infection from outside seems unlikely when strictly adhered to. As many new strains emerge worldwide during the course of on-going pandemic, the chances of re-infection cannot be ignored as it may contribute to false negative RT-PCR test results. SARS-2-CoV though a novel virus, is phylogenetically similar to SARS-like CoV with around 79% similarity. Studies on immunological response to these infections suggest that antibodies formed after infection confers immunity only for a short period of time before it starts to wane. Also studies on SARS-CoV-2 suggest that antibody formation and longevity of immunity in an individual is dependent on the strain of coronavirus, its severity and age of the person infected. All these considerations demand reviewing the treatment duration, discharge criteria, appropriate use of imaging techniques and importance of risk communication and health education to those recovered.
Databáze: OpenAIRE
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