Development of a minipig physical phantom from CT data
| Autor: | Sunhoo Park, Sehwan Shim, Young-Woo Jin, Sooyeun Park, Jae Seok Kim, Young-Su Kim, P. Lee, Chan Hyeong Kim, Han-Sung Kim, Wi-Ho Ha, Byeong Ryong Park |
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| Rok vydání: | 2017 |
| Předmět: |
Stereolithography
Swine Health Toxicology and Mutagenesis tissue-equivalent material Computed tomography Imaging phantom 030218 nuclear medicine & medical imaging physical phantom 03 medical and health sciences 0302 clinical medicine Animal model Imaging Three-Dimensional Technical Report Hounsfield scale Medicine Dosimetry Animals Radiology Nuclear Medicine and imaging Radiometry Radiation medicine.diagnostic_test business.industry Phantoms Imaging Soft tissue Treatment method minipig minipig physical phantom radiation dosimetry Organ Specificity 030220 oncology & carcinogenesis Swine Miniature business Tomography X-Ray Computed Effective atomic number Biomedical engineering |
| Zdroj: | Journal of Radiation Research |
| ISSN: | 1349-9157 |
| Popis: | Quantification of pathological progression of radiation-induced injury is essential in development of treatment methods, and a proper animal model is necessary for relevant radiological and medical studies. A minipig is a current animal model selected because of its similarities to humans in anatomy and pathology. In the present study, a minipig physical phantom was developed using computed tomography (CT) data. For dosimetry purposes, the minipig physical phantom was constructed on a slice-by-slice basis, with an array of holes to accommodate dosimeters. The phantom is constituted of three major organs, i.e. bone, lung, and remaining soft tissue, and the organs are clearly distinguishable on each 20-mm-thick axial slice. The quality of the tissue-equivalent (TE) substitutes was analyzed in terms of the atomic compositions and Hounsfield units (HUs). The density (in g/cm3) and effective atomic number of TE substitutes for the bone, lung, and soft tissue are 1.4 and 7.9, 0.5 and 10.0, and 1.0 and 5.9, respectively. Although the TE substitutes have slightly different physical properties, we think the phantom is acceptable because the HU values of the TE substitutes lie in the HU range of real tissues. |
| Databáze: | OpenAIRE |
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