Successful treatment of hypothalamic seizures and precocious puberty with GnRH analogue
| Autor: | Robert S. Greenwood, Michael B. Tennison, Megdad Zaatreh |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities medicine.medical_specialty Adolescent Hamartoma Antiepileptic drug Hypothalamus Puberty Precocious Gonadotropin-Releasing Hormone Epilepsy Hypothalamic hamartoma Internal medicine Gelastic seizure medicine Precocious puberty Humans In patient Child Brain Diseases business.industry medicine.disease Endocrinology Female Neurology (clinical) medicine.symptom business |
| Zdroj: | Neurology. 55(12) |
| ISSN: | 0028-3878 |
| Popis: | Article abstract Patients with hypothalamic hamartomas and precocious puberty may develop gelastic seizures that are resistant to conventional antiepileptic drug therapies. While treating precocious puberty in two such patients with long-acting GnRH analogue, the authors observed cessation of gelastic seizures. Although the mechanism is unclear, long-acting GnRH analogue should be considered as a possible therapy for gelastic seizures in patients with hypothalamic hamartomas. |
| Databáze: | OpenAIRE |
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