Synthesis and antimicrobial activity of bis(azolyl) urea derivatives

Autor:	Venkatapuram Padmavathi, Kayathi Narendra Babu, Tamatam Rekha, Grigory V. Zyryanov, G. Sravya, P. V. R. Reddy
Rok vydání:	2019
Předmět:	chemistry.chemical_classification Antifungal biology Base (chemistry) Chemistry medicine.drug_class Aspergillus niger Bacillus subtilis Antimicrobial biology.organism_classification Medicinal chemistry chemistry.chemical_compound medicine Urea Urea derivatives Antibacterial activity
Zdroj:	AIP Conf. Proc. AIP Conference Proceedings
ISSN:	0094-243X
DOI:	10.1063/1.5087354
Popis:	A variety of bis(azolyl) urea derivatives were prepared by the reaction of methyl benzazoyl carbamates with azolyl amines in the presence of mild base and studied their antimicrobial activity. The presence of electron donating substituents on the aromatic ring enhanced the activity. Methoxy substituted benzothiazolyl thiazolyl urea, benzothiazolyl imidazolyl urea and benzimidazolyl thiazolyl urea displayed prominent antibacterial activity against Bacillus subtilis. Benzothiazolyl imidazolyl urea and methyl substituted benzimidazolyl imidazolyl urea showed good antifungal activity against Aspergillus niger. © 2019 Author(s).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f713356cfa8982d7757553a165857e https://doi.org/10.1063/1.5087354 Zobrazit plný text záznamu