Impaired neutrophil chemotaxis after cardiac surgery
| Autor: | Merete Storgaard, Niels Obel, Rune Vedelsdal, Reinhold Jensen |
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| Rok vydání: | 1995 |
| Předmět: |
Male
medicine.medical_specialty Neutrophils Neutrophile Impaired neutrophil chemotaxis Anesthesia General Gastroenterology Blood Transfusion Autologous Leukocyte Count Cell Movement Internal medicine medicine Journal Article Humans Surgical Wound Infection Cardiac Surgical Procedures Coronary Artery Bypass Cardiopulmonary Bypass business.industry Research Support Non-U.S. Gov't Micropore Filters Extracorporeal circulation Chemotaxis Pathophysiology Peripheral Cardiac surgery N-Formylmethionine Leucyl-Phenylalanine Chemotaxis Leukocyte Elective Surgical Procedures Aortic Valve Immunology Absolute neutrophil count Mitral Valve Female Disease Susceptibility Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Jensen, R H, Storgaard, M, Vedelsdal, R & Obel, N 1995, ' Impaired neutrophil chemotaxis after cardiac surgery ' Scandinavian journal of thoracic and cardiovascular surgery, vol. 29, no. 3, pp. 115-8 . |
| ISSN: | 0036-5580 |
| Popis: | Chemotaxis of circulating peripheral neutrophils was studied in 12 patients undergoing elective cardiac surgery. Tests of neutrophil chemotaxis were made preoperatively and 16-20 hours postoperatively, using a multipore filter assay. Statistically significant postoperative decrease was demonstrated in both stimulated and random neutrophil migration (p = 0.012 and p = 0.009, respectively). Although the peripheral neutrophil count showed a statistically significant postoperative increase (p = 0.001), the increase did not correlate to the decrease in neutrophil chemotaxis. Nor could correlation be demonstrated between the altered neutrophil chemotaxis and any per- or postoperative variables. |
| Databáze: | OpenAIRE |
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