Factors Affecting Quality of Life at Different Intervals After Treatment of Localized Prostate Cancer: Unique Influence of Treatment Decision Making Satisfaction, Personality and Sexual Functioning

Autor: Shilajit Kundu, Benjamin D. Schalet, Nathaniel Sufrin, Michael McGuire, Brian T. Helfand, Stephanie A. Schuette, David Victorson, Charles B. Brendler, Kristian Novakovic
Přispěvatelé: Epidemiology and Data Science
Rok vydání: 2016
Předmět:
Zdroj: Victorson, D E, Schuette, S, Schalet, B D, Kundu, S D, Helfand, B T, Novakovic, K, Sufrin, N, McGuire, M & Brendler, C 2016, ' Factors Affecting Quality of Life at Different Intervals After Treatment of Localized Prostate Cancer : Unique Influence of Treatment Decision Making Satisfaction, Personality and Sexual Functioning ', The Journal of Urology, vol. 196, no. 5, pp. 1422-1428 . https://doi.org/10.1016/j.juro.2016.05.099
The Journal of Urology, 196(5), 1422-1428. Elsevier Inc.
ISSN: 1527-3792
0022-5347
DOI: 10.1016/j.juro.2016.05.099
Popis: PURPOSE: Using patient reported outcomes measures we identified the most informative set of factors associated with quality of life in a large sample of men treated for localized prostate cancer.MATERIALS AND METHODS: We examined relationships with quality of life using FACIT (Functional Assessment of Chronic Illness Therapy). We also hypothesized variables in a sample of men diagnosed with localized prostate cancer who represented different time points since treatment, including less than 12 months in 70, 1 to 3 years in 344, greater than 3 to 5 years in 291 and greater than 5 years in 97. Correlative measures included subscales of MAX-PC (Memorial Anxiety Scale for Prostate Cancer), short forms of PROMIS® and SOMS (Surgical Outcomes Measurement System), TDM-SATS (Treatment Decision-Making Satisfaction Scale) and subscales of the BFI (Big Five Inventory) of personality.RESULTS: Quality of life was significantly associated with hypothesized variables across different time cohorts. In regression models several factors accounted for most of the variability in quality of life scores depending on time since treatment, including 47%, 22%, 29% and 27% at less than 12 months, 1 to 3 years, greater than 3 to 5 years and greater than 5 years, respectively. Upon examining the unique contribution of these variables, treatment decision making satisfaction was the only variable to have a significant and unique contribution to quality of life across all 4 time cohorts (standardized coefficients 0.33, 0.27, 0.31 and 0.49, respectively, p CONCLUSIONS: When considering the short-term and the longer term quality of life of a man after treatment for localized prostate cancer, our findings highlight the importance of treatment decision making satisfaction, erectile function and personality.
Databáze: OpenAIRE