Growth of Staphylococcus aureus, Candida albicans, Escherichia coli and Pseudomonas aeruginosa in Propofol, Thiopental and a 1:1 Propofol-Thiopental Mixture

Autor: Cüneyt Özakin, Ayse Topal, Suna Gedikoğlu, Hulya Bilgin, Nihal Y. Gul
Přispěvatelé: Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Mikrobiyoloji Anabilim Dalı., Uludağ Üniversitesi/Veterinerlik Fakültesi/Klinik Bilimler Bölümü., Topal, Ayşe, Bilgin, Hülya, Özakın, Cüneyt, Gedikoğlu, Suna, Gül, Nihal Yaşar, A-7338-2016, AAG-8392-2021
Rok vydání: 2010
Předmět:
Zdroj: Journal of Animal and Veterinary Advances. 9:1432-1435
ISSN: 1680-5593
Popis: Extrinsic contamination of propofol is thought to be a source of postoperative sepsis. Researchers studied growth of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans in propofol, thiopental and in a 1:1 propofol-thiopental mixture. All microorganisms were taken from standard stock cultures. Half of the samples were incubated at 20 degrees C and the rest were stored at 4 degrees C for 120 h. Growth of microorganisms in each solution was compared by counting the number of the Colony-Forming Units (CFUs) at 0, 3, 6, 24, 72 and 120 h. Propofol supported the growth of all four microorganims at both temperatures. In contrast, thiopental and the 1:1 propofol-thiopental mixture exhibited markedly bactericidal properties on E. coli, C. albicans and P. aeruginosa and bacteriostatic effect on S. aureus.
Databáze: OpenAIRE