Meat consumption, related nutrients, obesity and risk of prostate cancer: A case-control study in Uruguay
| Autor: | Paolo Boffetta, Alvaro L. Ronco, Hugo Deneo-Pellegrini, Eduardo De Stefani |
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| Přispěvatelé: | De Stefani, E., Boffetta, P., Ronco, A.L., Deneo-Pellegrini, H. |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine Cancer Research medicine.medical_specialty Meat Epidemiology Logistic regression Role of meat consumption and related nutrients in the etiology of prostate cancer 03 medical and health sciences Prostate cancer 0302 clinical medicine Risk Factors Surveys and Questionnaires Environmental health Prevalence medicine Humans Obesity Aged Aged 80 and over Gynecology business.industry Public Health Environmental and Occupational Health Case-control study Prostatic Neoplasms food and beverages Odds ratio Middle Aged Prognosis medicine.disease Confidence interval Logistic Models 030104 developmental biology Oncology Quartile Food Case-Control Studies 030220 oncology & carcinogenesis Red meat Uruguay business Follow-Up Studies |
| Popis: | Background In order to determine the role of meat consumption and related nutrients in the etiology of prostate cancer we conducted a case-control study among Uruguayan men in the time period 1998-2007. Results The study included 464 cases and 472 controls, frequency matched for age and residence. Both series were drawn from the four major public hospitals in Montevideo. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95 % confidence intervals (95 % CI) of prostate cancer by quartiles of meat intake and related nutrients. The highest vs. the lowest quartile of intake of total meat (OR = 5.19, 95 % CI 3.46-7.81), red meat (OR = 4.64, 95 % CI 3.10-6.95), and processed meat (OR = 1.78, 95% CI 1.22-2.59) were associated with increased risk of prostate cancer. Meat nutrients were directly associated with the risk of prostate cancer (OR for cholesterol 5.61, 95 % CI 3.75-8.50). Moreover, both total meat and red meat displayed higher risks among obese patients. Conclusions This study suggests that total and red meat and meat nutrients may play a role in the etiology of prostate cancer in Uruguay. |
| Databáze: | OpenAIRE |
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