Data on prior pegylated liposomal doxorubicin (PLD) treatment in recurrent ovarian cancer: Post-hoc data analysis from the phase 3 randomized, open-label study comparing trabectedin and PLD versus PLD alone in patients with recurrent ovarian cancer
| Autor: | Scott Maul, Waleed Shalaby, Robert L. Coleman, Tracy McGowan, Bradley J. Monk, Thomas J. Herzog, George Wang, Roland Elmar Knoblauch, Spyros Triantos |
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| Rok vydání: | 2020 |
| Předmět: |
Response rate
Oncology medicine.medical_specialty Post hoc Combination therapy lcsh:Computer applications to medicine. Medical informatics Pegylated Liposomal Doxorubicin 03 medical and health sciences 0302 clinical medicine Open label study Pegylated liposomal doxorubicin Internal medicine Multicenter trial Medicine Overall survival In patient lcsh:Science (General) Trabectedin 030304 developmental biology 0303 health sciences Multidisciplinary business.industry Medicine and Dentistry enzymes and coenzymes (carbohydrates) Recurrent Ovarian Cancer lcsh:R858-859.7 lipids (amino acids peptides and proteins) Recurrent ovarian cancer business 030217 neurology & neurosurgery lcsh:Q1-390 medicine.drug |
| Zdroj: | Data in Brief Data in Brief, Vol 30, Iss, Pp 105465-(2020) |
| ISSN: | 2352-3409 |
| Popis: | The data presented herein are supplementary to our published primary article “A phase 3 randomized, open-label, multicenter trial for safety and efficacy of combined trabectedin and pegylated liposomal doxorubicin therapy for recurrent ovarian cancer”[1]. The exploratory analysis evaluated the impact of prior pegylated liposomal doxorubicin (PLD) therapy in patients who participated in a randomized, open-label study comparing combination therapy of trabectedin and PLD vs PLD alone in third-line recurrent ovarian cancer (ROC). These exploratory analyses showed that prior treatment with PLD in ROC does not impact the response and survival rates nor does it increase toxicities or negatively influence survival and response rates in both treatment groups. |
| Databáze: | OpenAIRE |
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