Multi-b value diffusion-weighted magnetic resonance imaging and intravoxel incoherent motion modeling: Differentiation of aggressive lymphoma lesions on initial treatment and activity assessment after chemotherapy
| Autor: | Qi Tang, Yan Rong, Yun-Ying Qin, Jian-Hong Zhong, Cheng-Cheng Liao, Qing Ke, Le-Qun Li, Hong Cen, Xiao-Hong Tan |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Lymphoma medicine.medical_treatment Aggressive lymphoma Sensitivity and Specificity Diagnostic Accuracy Study 03 medical and health sciences 0302 clinical medicine Image Interpretation Computer-Assisted diffusion weighted imaging Medicine Cutoff Effective diffusion coefficient Humans magnetic resonance imaging 030212 general & internal medicine Intravoxel incoherent motion Neoplasm Staging intravoxel incoherent motion Chemotherapy medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged medicine.disease Prognosis Diffusion Magnetic Resonance Imaging ROC Curve 030220 oncology & carcinogenesis Female Lymph cell diffusion business Nuclear medicine Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | The diagnostic efficiency of diffusion-weighted magnetic resonance imaging with different b-values and application of an intravoxel incoherent motion (IVIM) model for differentiating disease states of lymphoma was investigated. Thirty-six patients at initial diagnosis and 69 after chemotherapy underwent diffusion-weighted magnetic resonance imaging (DW-MRI) with multiple b-values. Analysis parameters included the apparent diffusion coefficient (ADC) for each b-value. Standard ADC, D, D∗, and f were calculated using an IVIM model. For patients at initial diagnosis, compared with aggressive lymphomas, the benign lymph nodes exhibited higher mean ADC (2.34 vs 0.66 × 10−3 mm2/s, P |
| Databáze: | OpenAIRE |
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