Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells reported in an asymptomatic patient: a rare case and literature review
| Autor: | Muhammad Siddique Khurram, Warda Ibrar, Ameer Hamza, Ramen Sakhi, Paul Mazzara |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
lcsh:Internal medicine
Pathology medicine.medical_specialty Malignant Pancreatic Neoplasm Pancreatic Neoplasms lcsh:Medicine Osteoclasts Adenocarcinoma Asymptomatic Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Osteoclast Internal Medicine medicine Carcinoma lcsh:RC31-1245 business.industry lcsh:R Mesenchymal stem cell medicine.disease Article / Clinical Case Report medicine.anatomical_structure Pancreatic Ductal Giant cell 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom Pancreas business Carcinoma Pancreatic Ductal |
| Zdroj: | Autopsy & Case Reports Autopsy and Case Reports, Vol 7, Iss 4 (2017) |
| ISSN: | 2236-1960 |
| DOI: | 10.4322/acr.2017.042 |
| Popis: | Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (UC-OGC) is a rare and poorly described pancreatic malignancy. It is comprised of mononuclear, pleomorphic, and undifferentiated cells as well as osteoclast-like giant cells (OGC’s). It constitutes less than 1% of pancreatic non-endocrine neoplasia and is twice as likely to occur in females as in males. Its histopathologic properties remain poorly understood. It is suspected that UC-OGC is of epithelial origin that can then transition to mesenchymal elements. As part of this study, we describe a case of a malignant pancreatic neoplasm that was discovered in a 69-year old patient as an incidental finding. We also provide an overview of previously published data to highlight UC-OGC’s clinical and pathologic features. |
| Databáze: | OpenAIRE |
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