Association of visit-to-visit blood pressure variability with the risk of all-cause mortality and cardiovascular events in general population
| Autor: | Yuling Yang, Lu Song, Liye Dai, Yongjun Wang, Xiaoli Li, Chunhui Li, Yilong Wang, Hualing Zhao, Shouling Wu, Xiaoming Zheng, Yuntao Wu |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty China Endocrinology Diabetes and Metabolism Population Blood Pressure 030204 cardiovascular system & hematology Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Cause of Death Internal Medicine Risk of mortality medicine Blood Pressure Variability Humans 030212 general & internal medicine education Aged Proportional Hazards Models Aged 80 and over education.field_of_study Analysis of Variance business.industry Proportional hazards model Confounding Hazard ratio Blood Pressure Determination Middle Aged Confidence interval Blood pressure Quartile Cardiovascular Diseases Population Surveillance Hypertension Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | J Clin Hypertens (Greenwich) |
| ISSN: | 1751-7176 |
| Popis: | The association between blood pressure variability (BPV) and the risk of all-cause mortality and cardiovascular diseases (CVD) is not well understood. The Kailuan study is a prospective longitudinal cohort study on cerebrovascular events and cardiovascular factors. In this study, resting blood pressure was measured at baseline and every 2 years from 2006 to 2007. BPV is mainly defined as the coefficient of variation (CV). Hazard ratio (HR), with 95% confidence intervals (CI) was calculated using Cox regression model. Among 52 387 participants, we identified 1817 who ended up with all-cause death and 1198 with CVD. Each 4.68% increase in BPV was associated with a 13% increase in the risk of mortality (HR = 1.13, 95% CI = 1.09-1.18) and a 7% increase in CVD (HR = 1.07, 95% CI = 1.02-1.13), respectively. After adjustment of confounding factors, the HR of comparing participants in the highest versus lowest quartile of CV of systolic blood pressure (SBP) was 1.37 (1.19, 1.57) for all-cause death, 1.18 (1.01, 1.39) for CVD. Similar results were also observed when BPV was measured by different parameters. We concluded that visit-to-visit BPV was associated with all-cause death and cardiovascular and cerebrovascular events in Chinese general population. |
| Databáze: | OpenAIRE |
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