Clinical investigation of atypical adenomatous hyperplasia of the lung
| Autor: | Kenji Eguchi, Yoshihiko Segawa, Mikiko Ida, Nagio Takigawa, Koichi Mandai, Hideyuki Saeki, Michihide Shimono, Daizo Kishino, Masao Nakata |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Cancer Research Pathology medicine.medical_specialty Lung Neoplasms Adenoma Adenocarcinoma Disease-Free Survival medicine Adenocarcinoma of the lung Humans Atypical adenomatous hyperplasia Stage (cooking) Aged Neoplasm Staging Aged 80 and over Hyperplasia Lung business.industry Smoking Respiratory disease Middle Aged Prognosis medicine.disease Survival Analysis medicine.anatomical_structure Oncology Female business Precancerous Conditions |
| Zdroj: | Lung Cancer. 25:115-121 |
| ISSN: | 0169-5002 |
| DOI: | 10.1016/s0169-5002(99)00055-0 |
| Popis: | The clinicopathologic characteristics of atypical adenomatous hyperplasia (AAH) remain unclear. A total of 137 patients underwent resection for adenocarcinoma of the lung at our institution. Examination of resected lung tissue showed that in addition to adenocarcinoma AAH was present in 26 cases and was not present in 111 cases. All nonsmokers with AAH ( n =13) had earlier-stage disease (stage IA, IB, IIA, and IIB) and no history of respiratory disease. Among patients with stage IA disease, the relapse-free and overall survival curves for those with AAH ( n =14) tended to be better than for those without AAH ( n =40), but the difference was not statistically significant ( P =0.056 and 0.087, respectively). Concurrent presence of AAH may be a favorable prognostic indicator in patients with stage IA adenocarcinoma. |
| Databáze: | OpenAIRE |
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