International Organism Profile of Periprosthetic Total Hip and Knee Infections
| Autor: | Nemandra A Sandiford, Martin Buttaro, Carlos A. Higuera, Daniel Rienzi, Jose Ignacio Oñativia, Jesus M. Villa, Daniel Kendoff, Nicolas S. Piuzzi, Ibrahim Theeb, Lisandro Carbo, Tejbir S. Pannu, S. A. Bozhkova, José Fregeiro, Nikolai N. Kornilov |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Prosthesis-Related Infections medicine.drug_class Arthroplasty Replacement Hip Antibiotics Periprosthetic medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Staphylococcus epidermidis Internal medicine medicine Humans Orthopedics and Sports Medicine Ohio Retrospective Studies 030222 orthopedics biology business.industry Incidence (epidemiology) Retrospective cohort study Staphylococcal Infections biology.organism_classification United Kingdom Anti-Bacterial Agents Europe Staphylococcus aureus North America Cohort Florida business |
| Zdroj: | The Journal of Arthroplasty. 36:274-278 |
| ISSN: | 0883-5403 |
| Popis: | There is scarce literature describing pathogens responsible for periprosthetic joint infections (PJIs) around the world. Therefore, we sought to describe periprosthetic joint infection causative organisms, rates of resistant organisms, and polymicrobial infections at 7 large institutions located in North/South America and Europe.We performed a retrospective study of 654 periprosthetic hip (n = 361) and knee (n = 293) infections (January 2006 to October 2019) identified at Cleveland Clinic Ohio/Florida in the United States (US) (n = 159), Hospital Italiano de Buenos Aires in Argentina (n = 99), Hospital Asociación Española in Uruguay (n = 130), Guy's and St Thomas' Hospital in the United Kingdom (UK) (n = 103), HELIOS Klinikum in Germany (n = 59), and Vreden Institute for Orthopedics in St. Petersburg, Russia (n = 104). Analyses were performed for the entire cohort, knees, and hips. Alpha was set at 0.05.Overall, the most frequent organisms identified were Staphylococcus aureus (24.8%) and Staphylococcus epidermidis (21.7%). The incidence of organisms resistant to at least one antibiotic was 58% and there was a significant difference between hips (62.3%) and knees (52.6%) (P = .014). Rates of resistant organisms among countries were 37.7% (US), 66.7% (Argentina), 71.5% (Uruguay), 40.8% (UK), 62.7% (Germany), and 77.9% (Russia) (P.001). The overall incidence of polymicrobial infections was 9.3% and the rates across nations were 9.4% in the US, 11.1% in Argentina, 4.6% in Uruguay, 4.9% in UK, 11.9% in Germany, and 16.3% in Russia (P = .026).In the evaluated institutions, S aureus and S epidermidis accounted for almost 50% of all infections. The US and the UK had the lowest incidence of resistant organisms while Germany and Russia had the highest. The UK and Uruguay had the lowest rates of polymicrobial infections. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect