Efficacy of the sphingosine-1-phosphate receptor agonist fingolimod in animal models of stroke: an updated meta-analysis

Autor:	Qian Li, Chunyang Wang, Xiaofeng Ma, Chun Dang, Yaoheng Lu
Rok vydání:	2020
Předmět:	Sphingosine 1 Phosphate Receptor Modulators 0301 basic medicine Agonist medicine.drug_class Sphingosine-1-phosphate receptor Ischemia Pharmacology Neuroprotection 03 medical and health sciences 0302 clinical medicine medicine Animals Humans cardiovascular diseases Sphingosine-1-Phosphate Receptors Stroke Neuroinflammation Fingolimod Hydrochloride business.industry General Neuroscience General Medicine medicine.disease Fingolimod Disease Models Animal Treatment Outcome 030104 developmental biology business Reperfusion injury 030217 neurology & neurosurgery medicine.drug
Zdroj:	International Journal of Neuroscience. 131:85-94
ISSN:	1543-5245 0020-7454
DOI:	10.1080/00207454.2020.1733556
Popis:	Objective: Neuroinflammation is a central part of cerebral ischemia/reperfusion injury. The novel immune suppressant, fingolimod, is a promising candidate to ameliorate stroke-induced damage. Fingo...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35a8bc0d0e5007bfe59aaf9fc961995 https://doi.org/10.1080/00207454.2020.1733556 Zobrazit plný text záznamu