Consensus Paper: Current Views on the Role of Cerebellar Interpositus Nucleus in Movement Control and Emotion

Autor: Alan R. Gibson, Vincenzo Perciavalle, Nadia L Cerminara, Agnès Gruart, José M. Delgado-García, Richard Apps, Vlastislav Bracha, Marinella Coco, Maria Leggio, Andrew J. Carrel, Raudel Sánchez-Campusano
Rok vydání: 2013
Předmět:
Zdroj: The Cerebellum. 12:738-757
ISSN: 1473-4230
1473-4222
DOI: 10.1007/s12311-013-0464-0
Popis: In the present paper, we examine the role of the cerebellar interpositus nucleus (IN) in motor and non-motor domains. Recent findings are considered, and we share the following conclusions: IN as part of the olivo-cortico-nuclear microcircuit is involved in providing powerful timing signals important in coordinating limb movements; IN could participate in the timing and performance of ongoing conditioned responses rather than the generation and/or initiation of such responses; IN is involved in the control of reflexive and voluntary movements in a task- and effector system-dependent fashion, including hand movements and associated upper limb adjustments, for quick effective actions; IN develops internal models for dynamic interactions of the motor system with the external environment for anticipatory control of movement; and IN plays a significant role in the modulation of autonomic and emotional functions.
Databáze: OpenAIRE