Lipoxygenase Inhibitors in the seeds of Aframomum danielli K. Schum (Zingiberaceae)
| Autor: | Peter J. Houghton, Olukemi A. Odukoya, Amala Raman |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Magnetic Resonance Spectroscopy
Zingiberales Pharmaceutical Science Alcohol Mass Spectrometry chemistry.chemical_compound Lipoxygenase Inhibitors Drug Discovery Humans Organic chemistry Pharmacology chemistry.chemical_classification biology Plant Extracts Aframomum biology.organism_classification Benzoquinone Enzyme Complementary and alternative medicine chemistry Phytylplastoquinone Seeds Molecular Medicine Zingiberaceae Chromatography Thin Layer Long chain |
| Zdroj: | Phytomedicine. 6:251-256 |
| ISSN: | 0944-7113 |
| DOI: | 10.1016/s0944-7113(99)80017-8 |
| Popis: | Summary Alcohol and petrol extracts of the seeds of Aframomum danielli inhibit the soya 5-lipoxygenase enzyme and thus may show antiinflammatory activity. Compounds isolated from the active fractions were shown to be long chain polyprenyl benzoquinone derivatives. Phytylplastoquinone was isolated from the petrol extract and plastoquinone-7 (heptaplastoquinone) from the alcohol extract. The presence of these two known benzoquinones in A. danielli and their ability to inhibit 5-lipoxygenase are reported here for the first time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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