Seroprevalence of hepatitis B virus infection and associated factors among prison inmates in state of Mato Grosso do Sul, Brazil
| Autor: | Alcione Cavalheiro Faro Stief, Paula Guerra Murat, Graciele Rodrigues Camolez, Regina Maria Bringel Martins, Roberta Barbosa Lopes Francisco, Sonia Maria Oliveira de Andrade, Sonia Maria Fernandes, Mauricio Antonio Pompilio, Ana Rita Coimbra Motta-Castro, Gina Jonasson Mousquer, Sheila Araújo Teles |
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| Rok vydání: | 2009 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty HBsAg Hepatitis B virus Adolescent Population Enzyme-Linked Immunosorbent Assay medicine.disease_cause Polymerase Chain Reaction Serology Young Adult Internal medicine Epidemiology Prevalence medicine Seroprevalence Humans Hepatitis B Antibodies education Aged education.field_of_study Hepatitis B Surface Antigens business.industry Prisoners Associated factors virus diseases Hepatitis B Middle Aged medicine.disease Hepatitis B Core Antigens digestive system diseases Infectious Diseases Prisons Immunology DNA Viral Educational Status Parasitology Female Viral hepatitis business Epidemiologic Methods Brazil |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical v.43 n.5 2010 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
| ISSN: | 1678-9849 |
| Popis: | INTRODUCTION: This study aimed to estimate the prevalence of HBV infection and associated factors among prison inmates in Campo Grande, MS. METHODS: A total of 408 individuals were interviewed regarding sociodemographic characteristics, associated factors and HBV vaccination using a standardized questionnaire. Blood samples were collected from all participants and serological markers for HBV were detected by enzyme-linked immunosorbent assay. Hepatitis B surface antigen (HBsAg) and/or antibodies against hepatitis B core antigen (anti-HBc) positive samples were tested for HBV-DNA by polymerase chain reaction. RESULTS: The overall prevalence of HBV infection was 17.9% (95%CI: 14.4-22.0). The HBsAg carrier rate was 0.5%; 56 (13.7%) individuals had been infected and developed natural immunity and 15 (3.7%) were positive for anti-HBc only. Ninety eight (24%) prisoners had only anti-HBs, suggesting that they had low vaccine coverage. An occult HBV infection rate of 0% was verified among anti-HBc-positive individuals. Multivariate analysis of associated factors showed that age > 35 years-old, low schooling level and illicit drug use are significantly associated with HBV infection. CONCLUSIONS: Analysis of the data showed HBV infection prevalence similar or slightly lower than that reported in other of Brazilian prisons. Independent predictors of HBV infection in this population include older age, low schooling level and illicit drug use. |
| Databáze: | OpenAIRE |
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