Time From Smoking Cessation and Inflammatory Markers: New Evidence From a Cross-Sectional Analysis of ELSA-Brasil
| Autor: | Antonio Luiz Pinho Ribeiro, Sandhi Maria Barreto, Bruce Bartholow Duncan, Luana Giatti, Lidyane do Valle Camelo, Flávia Soares Peres, Pedro Guatimosim Vidigal |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Longitudinal study Time Factors Cross-sectional study medicine.medical_treatment 030204 cardiovascular system & hematology Leukocyte Count 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Internal medicine medicine Humans Longitudinal Studies 030212 general & internal medicine Aged COPD biology business.industry Smoking C-reactive protein Confounding Public Health Environmental and Occupational Health Middle Aged medicine.disease Former Smoker C-Reactive Protein Cross-Sectional Studies Linear Models biology.protein Smoking cessation Female Smoking Cessation business Biomarkers Brazil |
| Zdroj: | Nicotine & Tobacco Research. 19:852-858 |
| ISSN: | 1469-994X 1462-2203 |
| DOI: | 10.1093/ntr/ntx032 |
| Popis: | Introduction The time for inflammatory markers of former smokers to revert to never smoker levels is still controversial, ranging from 5 to 20 years. We aimed to determine the time from smoking cessation for white blood cell (WBC) count and serum C-reactive protein (CRP) levels to return to those of never-smokers, after adjusting for confounding factors and for secondhand smoke (SHS) exposure among participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods Cross-sectional analysis of baseline participants of ELSA-Brasil. We used linear regression analysis and generalized linear models with gamma distribution and logarithmic link function to estimate the association of WBC count and CRP levels with time from smoking cessation. The following confounding factors were considered: sex, age, education, SHS, alcohol consumption, leisure-time physical activity, BMI, total cholesterol/HDL ratio, hypertension, diabetes, cardiovascular disease, and chronic obstructive pulmonary disease (COPD). Results: After all adjustments, time from smoking cessation |
| Databáze: | OpenAIRE |
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