Thank ORP9 for FFAT: With endosomal ORP10, it's fission accomplished!

Autor: Louise H. Wong, Andrea Martello, Emily R. Eden
Rok vydání: 2021
Předmět:
Zdroj: The Journal of cell biology. 221(1)
ISSN: 1540-8140
Popis: Heterogeneity in endosomal membrane phospholipid content is emerging as a regulator of endocytic trafficking pathways. Kawasaki et al. (2021. J. Cell. Biol.https://doi.org/10.1083/jcb.202103141) demonstrate exchange of endosomal PI4P for PS by ORP10 at ER–endosome contact sites, with the consequent recruitment of endosomal fission factors.
Databáze: OpenAIRE