Comparative Analyses of Tumour Volume Doubling Times for Periocular and Non-periocular Head and Neck Basal Cell Carcinomas
| Autor: | Holger Sudhoff, Andre Boo Shern Khoo, Peter K. C. Goon, Patrick Kin Cho Goon |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Pathology medicine.medical_specialty Skin Neoplasms Time Factors Dermatology Eyelid Neoplasms Malignancy Cohort Studies medicine lcsh:Dermatology Humans Periocular Region Doubling time Neoplasm Invasiveness Basal cell carcinoma Basal cell Head and neck tumour volume doubling time Aged Retrospective Studies business.industry Biopsy Needle growth rates General Medicine Middle Aged lcsh:RL1-803 Mohs Surgery medicine.disease Immunohistochemistry eye diseases Tumor Burden Carcinoma Basal Cell Head and Neck Neoplasms periocular Female Tumour volume sense organs non-periocular head and neck basal cell carcinoma bccs business Follow-Up Studies |
| Zdroj: | Acta Dermato-Venereologica, Vol 99, Iss 13, Pp 1266-1269 (2019) |
| Popis: | Basal cell carcinomas are the commonest solid malignancy in humans and thought to grow faster in the periocular region. We measured growth rates between periocular and non-periocular nodular basal cell carcinomas in the head and neck region from high-resolution digital photos and operative notes. The non-periocular basal cell carcinomas (head and neck) showed a mean tumour volume doubling time of 129.8 ± 21.74 (n = 79) days, and the periocular basal cell carcinoma a mean of 177.5 ± 37.21 (n = 47) days. The unpaired t-test with Welch correction showed that this difference was not significant (p = 0.2719). The mean tumour volume doubling time was 147.59 ± 37.75 days for head and neck basal cell carcinomas overall. For the first time, tumour volume doubling times for nodular basal cell carcinomas in the periocular versus non-periocular regions for the head and neck area were analysed, with no significant differences demonstrated. Further, comparison of basal cell carcinoma growth rates with other common solid tumours confirmed that basal cell carcinomas are slow growing malignancies. |
| Databáze: | OpenAIRE |
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